Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | Set_03_truncNotch_versus_wtNotch.phenotype_truncNotch_versus_wtNotch.cls #truncNotch_versus_wtNotch |
| Phenotype | phenotype_truncNotch_versus_wtNotch.cls#truncNotch_versus_wtNotch |
| Upregulated in class | wtNotch |
| GeneSet | BIOCARTA_SKELETAL MUSCLE HYPERTROPHY IS REGULATED VIA AKT-MTOR PATHWAY |
| Enrichment Score (ES) | -0.7737311 |
| Normalized Enrichment Score (NES) | -1.5625323 |
| Nominal p-value | 0.015837105 |
| FDR q-value | 0.519222 |
| FWER p-Value | 0.963 |
| PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|---|
| 1 | RPS6 | 2060168 | 2149 | 0.196 | -0.0851 | No | ||
| 2 | MKNK1 | 6510161 | 2208 | 0.189 | -0.0587 | No | ||
| 3 | IGF1R | 3360494 | 2645 | 0.138 | -0.0606 | No | ||
| 4 | EIF4E | 1580403 70133 6380215 | 3677 | 0.069 | -0.1052 | No | ||
| 5 | FRAP1 | 2850037 6660010 | 3862 | 0.062 | -0.1054 | No | ||
| 6 | IGF1 | 1990193 3130377 3290280 | 4128 | 0.053 | -0.1114 | No | ||
| 7 | EIF2B5 | 430315 6900400 | 5773 | 0.023 | -0.1962 | No | ||
| 8 | PIK3R1 | 4730671 | 9416 | 0.004 | -0.3915 | No | ||
| 9 | RPS6KB1 | 1450427 5080110 6200563 | 10168 | 0.002 | -0.4316 | No | ||
| 10 | AKT1 | 5290746 | 11364 | -0.002 | -0.4956 | No | ||
| 11 | EIF4EBP1 | 60132 5720148 | 12913 | -0.008 | -0.5777 | No | ||
| 12 | PIK3CA | 6220129 | 13948 | -0.016 | -0.6308 | No | ||
| 13 | EIF2S1 | 5360292 | 14435 | -0.023 | -0.6533 | No | ||
| 14 | PDK2 | 2690017 | 15428 | -0.056 | -0.6980 | No | ||
| 15 | PDPK1 | 6650168 | 16837 | -0.204 | -0.7419 | Yes | ||
| 16 | GSK3B | 5360348 | 17003 | -0.232 | -0.7146 | Yes | ||
| 17 | PTEN | 3390064 | 17115 | -0.256 | -0.6806 | Yes | ||
| 18 | EIF4A1 | 1990341 2810300 | 17709 | -0.427 | -0.6458 | Yes | ||
| 19 | EIF4G1 | 4070446 | 17816 | -0.472 | -0.5778 | Yes | ||
| 20 | PABPC1 | 2650180 2690253 6020632 1990270 | 17866 | -0.488 | -0.5041 | Yes | ||
| 21 | INPPL1 | 110717 3120164 | 17906 | -0.509 | -0.4267 | Yes | ||
| 22 | EIF2S2 | 770095 2810487 | 18392 | -0.876 | -0.3161 | Yes | ||
| 23 | PPP2R5D | 4010156 380408 5550112 5670162 | 18449 | -0.968 | -0.1680 | Yes | ||
| 24 | PSMC4 | 580050 1580025 | 18506 | -1.133 | 0.0059 | Yes |
